The Darwin Droid has crunched its data and spit out a set of predictions. This week we’ve decided to show our picks before the games. Below are the selected predictions:
| Visitor | Home | Predicted Winner |
| Denver Broncos | San Diego Chargers | Denver Broncos |
| Baltimore Ravens | New York Gians | New York Giants |
| Carolina Panthers | New Orleans Saints | New Orleans Saints |
| Cincinnati Bengals | New England Patriots | New England Patriots |
| Cleveland Browns | Tennessee Titans | Tennessee Titans |
| Jacksonville Jaguars | Chicago Bears | Jacksonville Jaguars |
| Los Angeles Rams | Detroit Lions | Detroit Lions |
| Philadelphia Eagles | Washington Redskins | Philadelphia Eagles |
| Pittsburgh Steelers | Miami Dolphins | Miami Dolphins |
| San Fransico 49ers | Buffalo Bills | San Fransisco 49ers |
| Kansas City Chiefs | Oakland Raiders | Kansas City Chiefs |
| Atlanta Falcons | Seattle Seahawks | Atlanta Falcons |
| Dallas Cowboys | Green Bay Packers | Green Bay Packers |
| Indianapolis Colts | Houston Texans | Houston Texans |
| New York Jets | Arizona Cardinals | Arizona Cardinals |